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L-glutamine for dogs – An Amazing Dog Supplement

  • 6 min read

Dogs suffer from diarrhoea as a result of inflammation of the small and large intestines, tumours, stress, parasites, and the introduction of a new diet.

Most times antibiotics and corticosteroids are prescribed by experts to remedy these conditions. Apart from antibiotics and corticosteroids, natural therapy is known as L-Glutamine, amino acid can also help soothe the digestive tract and cure diarrhoea.

Glutamine is formed in the muscles and then it is moved from the muscles to the other parts of the body. It is also the most abundant amino acid available in the body system. 

This amino acid glutamine is required in making other amino acids and glucose. It is also a building block for making proteins in the body.

Supplements from Glutamine can aid gut functionality, boost the immune system and other benefits. This is mostly important during stress because the body would ordinarily use more Glutamine. 

Glutamine is also important in helping wound healing. The indispensability of Glutamine in cell division could be reflected in its high level, in the blood and intestinal lining.

While L-glutamine supplementation is used in treating cancer for humans, its levels are often reduced in cancerous situations. It also lowers as a result of chemotherapy.

Glutamine protects normal cells from chemotherapy effects and aids dying of cancer cells.

It is also a readily attainable amino acid (Glutamine and L-Glutamine), in terms of bodybuilders. Glutamine is easily found in most major sources of food which are equally rich in proteins.

These include:

  •  Beans  
  • Cabbage
  • Beets
  • Dairy products
  • Eggs
  • Chicken
  • Milk

Differentiating between Glutamine and L-Glutamine

Glutamine is an amino acid while L-glutamine is an isomer of glutamine. This is the major difference between glutamine and L-glutamine.

Common amino acids are twenty in number. Amino acids are simple molecules formulated with C, H, O, N and possibly S. Amino acids all have a –COOH, NH2 groups, a –H bonded to a carbon.

The R group is different from amino acid to amino acid. The R group is also a hydrogen atm called glycine in the simplest amino acid form.   

Many of these amino acids are needful to humans, but some others are not. One of the non-essential amino acids is glutamine.

However, L-glutamine is among two isomers of protein, but glutamine is made up of two non-superimposable isomers as D-isomer and L-isomer.  

Glutamine is also a hydrophilic amino acid found in almost all proteins. These are the major differences when you compare glutamine and L-glutamine.   

Also, L-glutamine boasts of more essential applications, compared with D-isomer. It is equally useful for supplementing diets and boosting gut immune functions, among others.

As an amino acid in human blood, glutamine is one of the most abundant.

Reasons to recommend administration of glutamine to pets

The amino acid glutamine is always recommended for pets with parvovirus enteritis and chronic bowel disorders like inflammatory bowel disease. This is because it is the preferred fuel source of intestinal epithelial cells that are damaged.

Too much exercise, infection, surgery and trauma are also capable of depleting glutamine reserves in the body, especially in muscle cells.

It can minimize inflammation of the intestinal tract because of radiation therapy, and might also reduce the gastrointestinal toxicity of a number of chemotherapy drugs.

Glutamine might also be a useful adjunct treatment to benefit pets that has leaky gut syndrome. In this case, increased intestinal permeability can cause the development of food allergies or intolerances.  

L-Glutamine is a natural alternative

The amino acid L-Glutamine is gotten from glutamic acid derived from high-protein –foods like dairy products, fish, meat and beans.

On the other hand, a deficiency in L-Glutamine is capable of affecting the digestive tract, muscle cells and the overall immune system.  

When a dog suffers from diarrhoea, like a situation of chronic inflammatory bowel disease, he/she might require additional L-Glutamine to help in replacing cells, lining the intestinal tract.

On the other hand, dogs that exercise regularly might also need L-glutamine to help in replacing muscle cells.  

L-Glutamine supplement is safe  

If taken in recommended doses, L-glutamine is known to be a safe supplement for dogs. It is also a naturally occurring amino acid available in the body system.

Moreover, dogs on anti-epilepsy drugs shouldn’t have glutamine administered on them, except the dog is closely watched by a veterinarian. This is because epilepsy drugs work by blocking Glutamine stimulation in the brain.

When it comes to digestive problems, administering L- glutamine has no immediate effect, but it rather helps to gradually improve the condition within a period of weeks.   

Best ways of feeding L-Glutamine to dogs

The L-glutamine amino acid helps the gut in regenerating and adsorbing nutrients appropriately. Enzymes’ deviancy leads to digestive disease in dogs.

Your dog’s digestive lining and organs functionality might become impaired if your dog has suffered pancreatitis, colitis and irritable bowel like symptoms.     

To administer L-glutamine to your dog, start with small doses and increase it gradually. You can give giant dog breeds a 2g dose per day. Give large dogs a 1.5g twice a day, and to your medium-sized dogs, give a 1g dose two times a day. Only 0.5g measurement twice daily would be alright for your small dogs.

Issue of Prescription and where to get L-Glutamine

Supplements are not much regulated and dog owners should be cautious, to avoid buying supplements that do not come with a labelled quantity of ingredients or buying without the knowledge of the manufacturer.

Why not consult an expert to recommend better-referred brands of supplements?  


Glutamine is not meant to treat, diagnose, cure and prevent dog disease. Don’t also forget to keep it in a dry and cool place.  

Glutamine shouldn’t be fed to your dog if he/she is on anti-convulsant medication. Overdose of glutamine might also be risky to pets with epilepsy.


In conclusion, L-glutamine and glutamine are natural therapies that can be used for your dog to overcome some diseases and conditions. To make utmost use of them, however, you have to abide by the instructions concerning their use.

Note: these tips are just for informational purposes only. We advise you to consult your vet often, concerning your pet’s well-being.